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Tag: HIV drug interaction

Protease Inhibitors and St. John’s Wort: Why This Herbal Mix Can Cause HIV Treatment Failure
  • By Andy Dargon
  • 16 Jan 2026

Protease Inhibitors and St. John’s Wort: Why This Herbal Mix Can Cause HIV Treatment Failure

St. John’s Wort can slash HIV protease inhibitor levels by up to 81%, leading to treatment failure and drug resistance. This interaction is well-documented, dangerous, and still happening-despite decades of warnings.

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