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Triptans and SSRIs: The Truth Behind the Serotonin Syndrome Myth
  • By Andy Dargon
  • 20 Mar 2026

Triptans and SSRIs: The Truth Behind the Serotonin Syndrome Myth

Despite a 2006 FDA warning, combining triptans for migraines with SSRIs for depression is safe. Real-world data shows zero cases of serotonin syndrome, yet the myth persists-leaving millions without effective treatment.

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