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Tag: opioid metabolism

Codeine and CYP2D6 Ultrarapid Metabolizers: What You Need to Know About Overdose Risk
  • By Andy Dargon
  • 3 Jan 2026

Codeine and CYP2D6 Ultrarapid Metabolizers: What You Need to Know About Overdose Risk

Codeine can cause fatal overdoses in people with a genetic variation called CYP2D6 ultrarapid metabolism. Learn who's at risk, what symptoms to watch for, and safer alternatives to avoid life-threatening reactions.

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