Irbesartan: what it does and who should take it

Irbesartan is a prescription medicine that lowers blood pressure and protects kidneys in people with type 2 diabetes and high blood pressure. It’s part of a drug class called angiotensin II receptor blockers (ARBs). If your doctor prescribed irbesartan, you’re probably trying to control blood pressure or slow kidney damage. This page gives clear, practical info so you know how to use it safely and what to watch for.

How to take irbesartan

Most adults start on 150 mg once a day. If needed, doctors may increase the dose to 300 mg daily. Take it at the same time each day — morning or evening — with or without food. If you miss a dose, take it as soon as you remember unless it’s close to your next dose. Don’t double up.

For diabetic kidney protection, your doctor might choose specific doses and schedule lab checks. Keep all follow-up visits so your provider can adjust the dose based on your blood pressure and kidney tests.

Side effects, monitoring and interactions

Common side effects include dizziness, tiredness, and mild stomach upset. Dizziness often happens when you stand up quickly — get up slowly. More serious issues are rare but important: high potassium (hyperkalemia), worsening kidney function, low blood pressure, and allergic reactions. If you feel faint, have swelling, or notice decreased urine, contact your provider.

Your doctor will likely check blood pressure, kidney function (creatinine), and potassium levels before starting irbesartan and again a few weeks after any dose change. People with kidney artery narrowing, severe dehydration, or low blood pressure may need closer monitoring or a different drug. Never use irbesartan during pregnancy — it can seriously harm the fetus.

Drug interactions to watch for: avoid combining irbesartan with ACE inhibitors unless closely managed by a specialist — that combo raises the risk of kidney problems and high potassium. Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce blood pressure control and increase kidney risk. Potassium supplements, salt substitutes with potassium, and lithium may interact, so tell your doctor about all medicines and supplements you take.

Want to save on costs? Ask your provider about generic irbesartan — it’s widely available and cheaper. If you shop online, use licensed pharmacies, keep your prescription, and compare prices safely. Avoid sites that sell prescription drugs without asking for a prescription.

Questions to ask your doctor: What target blood pressure should I aim for? How often will you check my kidneys and potassium? Can I take my other meds with irbesartan? Clear answers to these make using the drug safer and more effective.

If symptoms or lab results worry you, call your healthcare team. Irbesartan is a useful, well-tolerated option for many people with high blood pressure or diabetic kidney disease when used under medical supervision.